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PGD Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR09071G 100 μl / $495

PGD Antibody (Center)

Brand

Leading Biology

Catalog Number

APR09071G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PGD antibody (Center).

Molecular Weight

53140 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

236-265 aa

Target

This PGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the Central region of human PGD.

Isotype

Rabbit Ig

Symbol

PGDH

GeneID

UniProt ID

Function

Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.

Summary

6-phosphogluconate dehydrogenase is the seconddehydrogenase in the pentose phosphate shunt. Deficiency of thisenzyme is generally asymptomatic, and the inheritance of thisdisorder is autosomal dominant. Hemolysis results from combineddeficiency of 6-phosphogluconate dehydrogenase and6-phosphogluconolactonase suggesting a synergism of the twoenzymopathies.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

6-phosphogluconate dehydrogenase, decarboxylating, PGD, PGDH

Images

PGD Antibody (Center) (Cat. APR09071G) western blot analysis in 293,MCF-7 cell line lysates (35ug/lane).This demonstrates the PGD antibody detected PGD protein (arrow).

PGD Antibody (Center) (Cat. APR09071G) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the PGD antibody detected PGD protein (arrow).

PGD Antibody (Center) (Cat. APR09071G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PGD Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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