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B4GALT5 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APG02156G 100 μl / $495

B4GALT5 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APG02156G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality B4GALT5 antibody (C-term).

Molecular Weight

45119 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

324-350 aa

Target

This B4GALT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-350 amino acids from the C-terminal region of human B4GALT5.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

Summary

This gene is one of seven beta-1,4-galactosyltransferase(beta4GalT) genes. They encode type II membrane-bound glycoproteinsthat appear to have exclusive specificity for the donor substrateUDP-galactose; all transfer galactose in a beta1,4 linkage tosimilar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has adistinct function in the biosynthesis of different glycoconjugatesand saccharide structures. As type II membrane proteins, they havean N-terminal hydrophobic signal sequence that directs the proteinto the Golgi apparatus and which then remains uncleaved to functionas a transmembrane anchor. By sequence similarity, the beta4GalTsform four groups: beta4GalT1 and beta4GalT2, beta4GalT3 andbeta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The functionof the enzyme encoded by this gene is not clear. This gene waspreviously designated as B4GALT4 but was renamed to B4GALT5. In theliterature it is also referred to as beta4GalT2. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Beta-1, 4-galactosyltransferase 5, Beta-1, 4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 241-, Beta-1, 4-GalT II, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, B4GALT5

Images

B4GALT5 Antibody (C-term)(Cat. APG02156G) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the B4GALT5 antibody detected B4GALT5 protein (arrow).

B4GALT5 Antibody (C-term) (Cat. APG02156G) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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