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mGluR6 Antibody

Catalog # Availability Size / Price Inquiry
AMM06393G 100 μl / $495

mGluR6 Antibody

Brand

Leading Biology

Catalog Number

AMM06393G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality mGluR6 antibody.

Molecular Weight

95 KDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

850-877 aa

Symbol

GPRC1F, MGLUR6

GeneID

UniProt ID

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.

Summary

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Dilution

WB~~ 1:1000 IHC~~1:50-1:100

Synonyms

Metabotropic glutamate receptor 6, mGluR6, GRM6, GPRC1F, MGLUR6

Images

Western blot analysis of lysates from K562 cell line ,using mGluR6 Antibody(C0210). C0210 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug.

Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR6 antibody .

Specification

Quantity

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