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LPPR4 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR12455G 100 μl / $495

LPPR4 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR12455G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LPPR4 antibody (C-term).

Molecular Weight

82983 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

666-695 aa

Target

This LPPR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human LPPR4.

Isotype

Rabbit Ig

Symbol

KIAA0455, PRG1

GeneID

UniProt ID

Function

Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus.

Summary

LPPR4 belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Lipid phosphate phosphatase-related protein type 4, Brain-specific phosphatidic acid phosphatase-like protein 1, Plasticity-related gene 1 protein, PRG-1, LPPR4, KIAA0455, PRG1

Images

LPPR4 Antibody (C-term) (Cat. APR12455G) western blot analysis in Hela,Jurkat,NCI-H460 cell line lysates (35ug/lane).This demonstrates the LPPR4 antibody detected the LPPR4 protein (arrow).

LPPR4 Antibody (C-term) (Cat. APR12455G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LPPR4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

LPPR4 Antibody (C-term) (Cat. APR12455G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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