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Polyclonal Antibodies >
Phospho-SLAMF1(Y281) AntibodyBrand |
Leading Biology | Catalog Number |
APR11161G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-SLAMF1(Y281) antibody.
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Molecular Weight |
37231 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
This SLAMF1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1.
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Isotype |
Rabbit Ig
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Symbol |
SLAM
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GeneID |
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UniProt ID |
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Function |
High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
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Summary |
SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
DB, E
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Dilution |
DB~~1:500
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Synonyms |
Signaling lymphocytic activation molecule, CDw150, IPO-3, CD150, SLAMF1, SLAM
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Images |
Dot blot analysis of anti-Phospho-SLAMF1-pY281 Antibody (Cat. APR11161G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
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Specification |
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Quantity |
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