> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > QKI Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR13034G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality QKI antibody (N-term).
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Molecular Weight |
37671 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This QKI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human QKI.
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Isotype |
Rabbit Ig
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Symbol |
HKQ
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GeneID |
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UniProt ID |
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Function |
RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
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Summary |
QKI belongs to a family of RNA-binding proteins that have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, WB, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Protein quaking, Hqk, HqkI, QKI, HKQ
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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