> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MRI1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR08513G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MRI1 antibody (Center).
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Molecular Weight |
39150 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus {ECO:0000255|HAMAP-Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cytoplasm {ECO:0000255|HAMAP- Rule:MF_03119, ECO:0000269|PubMed:19620624}. Cell projection. Note=Primarily nuclear, but cytoplasmic in cancer cells, with enrichment at leading edge of the plasma membrane in late stage tumor cells
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
This MRI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human MRI1.
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Isotype |
Rabbit Ig
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Symbol |
MRDI
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GeneID |
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UniProt ID |
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Function |
Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
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Summary |
Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:8000
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Synonyms |
Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, M1Pi {ECO:0000255|HAMAP-Rule:MF_03119}, MTR-1-P isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, 5.3.1.23 {ECO:0000255|HAMAP-Rule:MF_03119}, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255|HAMAP-Rule:MF_03119}, MRI1 {ECO:0000255|HAMAP-Rule:MF_03119}, MRDI
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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