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PTPRZ1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR13029G 100 μl / $495

PTPRZ1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR13029G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPRZ1 antibody (N-term).

Molecular Weight

254587 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Secreted. Note=A secreted form is apparently generated by shedding of the extracellular domain

Host

Rabbit

Species Reactivity

Human

Target

This PTPRZ1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 446-480 amino acids from the N-terminal region of human PTPRZ1.

Isotype

Rabbit Ig

Symbol

HTPZP2, PTPRZ, PTPRZ2, PTPZ

GeneID

UniProt ID

Function

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity).

Summary

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Receptor-type tyrosine-protein phosphatase zeta, R-PTP-zeta, Protein-tyrosine phosphatase receptor type Z polypeptide 1, Protein-tyrosine phosphatase receptor type Z polypeptide 2, R-PTP-zeta-2, PTPRZ1, HTPZP2, PTPRZ, PTPRZ2, PTPZ

Images

Western blot analysis of lysate from human brain tissue lysate, using PTPRZ1 Antibody (N-term)( APR13029G). APR13029G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Specification

Quantity

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