> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ISCU Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR08057G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ISCU antibody (C-term).
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Molecular Weight |
17999 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Mitochondrion.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
138-167 aa
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Target |
This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
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Isotype |
Rabbit Ig
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Symbol |
NIFUN
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GeneID |
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UniProt ID |
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Function |
Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron.
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Summary |
Iron-sulfur (Fe-S) clusters are necessary for severalmitochondrial enzymes and other subcellular compartment proteins.They contain sulfur and iron, and are created via several stepsthat include cysteine desulfurases, iron donors, chaperones, andscaffold proteins. This gene encodes the two isomeric forms, ISCU1and ISCU2, of the Fe-S cluster scaffold protein. Mutations in thisgene have been found in patients with myopathy with severe exerciseintolerance and myoglobinuria.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN
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Images |
ISCU Antibody (C-term) (Cat. APR08057G) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).
ISCU Antibody (C-term) (Cat. APR08057G) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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