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ISCU Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR08057G 100 μl / $495

ISCU Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR08057G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ISCU antibody (C-term).

Molecular Weight

17999 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Mitochondrion.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

138-167 aa

Target

This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.

Isotype

Rabbit Ig

Symbol

NIFUN

GeneID

UniProt ID

Function

Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron.

Summary

Iron-sulfur (Fe-S) clusters are necessary for severalmitochondrial enzymes and other subcellular compartment proteins.They contain sulfur and iron, and are created via several stepsthat include cysteine desulfurases, iron donors, chaperones, andscaffold proteins. This gene encodes the two isomeric forms, ISCU1and ISCU2, of the Fe-S cluster scaffold protein. Mutations in thisgene have been found in patients with myopathy with severe exerciseintolerance and myoglobinuria.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN

Images

ISCU Antibody (C-term) (Cat. APR08057G) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).

ISCU Antibody (C-term) (Cat. APR08057G) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ISCU antibody detected the ISCU protein (arrow).

Specification

Quantity

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