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MMACHC Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR08479G 100 μl / $495

MMACHC Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR08479G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMACHC antibody (C-term).

Molecular Weight

31728 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

239-267 aa

Target

This MMACHC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human MMACHC.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).

Summary

The exact function of the protein encoded by this gene isnot known, however, its C-terminal region shows similarity to TonB,a bacterial protein involved in energy transduction for cobalamin(vitamin B12) uptake. Hence, it is postulated that this protein mayhave a role in the binding and intracellular trafficking ofcobalamin. Mutations in this gene are associated with methylmalonicaciduria and homocystinuria type cblC.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Methylmalonic aciduria and homocystinuria type C protein, MMACHC

Images

MMACHC Antibody (C-term) (Cat. APR08479G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MMACHC antibody detected the MMACHC protein (arrow).

Specification

Quantity

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