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HPS5 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR16710G 100 μl / $495

HPS5 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR16710G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HPS5 antibody (N-term).

Molecular Weight

127449 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Immunogen

88-116 aa

Target

This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.

Isotype

Rabbit Ig

Symbol

AIBP63, KIAA1017

GeneID

UniProt ID

Function

May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.

Summary

This gene encodes a protein that may play a role inorganelle biogenesis associated with melanosomes, platelet densegranules, and lysosomes. This protein interacts withHermansky-Pudlak syndrome 6 protein and may interact with thecytoplasmic domain of integrin, alpha-3. Mutations in this gene areassociated with Hermansky-Pudlak syndrome type 5. Multipletranscript variants encoding two distinct isoforms have beenidentified for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Hermansky-Pudlak syndrome 5 protein, Alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2, HPS5, AIBP63, KIAA1017

Images

HPS5 Antibody (N-term) (Cat. APR16710G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HPS5 antibody detected the HPS5 protein (arrow).

Specification

Quantity

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