> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SCNN1B Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMR09830G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SCNN1B antibody (Center).
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Molecular Weight |
72659 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
306-332 aa
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Target |
This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
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Summary |
Nonvoltage-gated, amiloride-sensitive, sodium channelscontrol fluid and electrolyte transport across epithelia in manyorgans. These channels are heteromeric complexes consisting of 3subunits: alpha, beta, and gamma. This gene encodes the betasubunit, and mutations in this gene have been associated withpseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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