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SPINT2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR13509G 100 μl / $495

SPINT2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR13509G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPINT2 antibody (C-term).

Molecular Weight

28228 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

222-251 aa

Target

This SPINT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human SPINT2.

Isotype

Rabbit Ig

Symbol

HAI2, KOP

GeneID

UniProt ID

Function

Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.

Summary

This gene encodes a transmembrane protein with twoextracellular Kunitz domains that inhibits a variety of serineproteases. The protein inhibits HGF activator which prevents theformation of active hepatocyte growth factor. This gene is aputative tumor suppressor, and mutations in this gene result incongenital sodium diarrhea. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Kunitz-type protease inhibitor 2, Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin, SPINT2, HAI2, KOP

Images

SPINT2 Antibody (C-term)(Cat. APR13509G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SPINT2 antibody detected the SPINT2 protein (arrow).

Specification

Quantity

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