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RREB1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM07668G 100 μl / $495

RREB1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM07668G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RREB1 antibody (C-term).

Molecular Weight

181420 Da

Cellular Localization

Antigen Cellular Localization: Nucleus speckle

Host

Rabbit

Species Reactivity

Human

Immunogen

1398-1424 aa

Target

This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.

Isotype

Rabbit Ig

Symbol

FINB

GeneID

UniProt ID

Function

Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.

Summary

The protein encoded by this gene is a zinc fingertranscription factor that binds to RAS-responsive elements (RREs)of gene promoters. It has been shown that the calcitonin genepromoter contains an RRE and that the encoded protein binds thereand increases expression of calcitonin, which may be involved inRas/Raf-mediated cell differentiation. Multiple transcript variantsencoding several different isoforms have been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB

Images

RREB1 Antibody (C-term) (Cat. AMM07668G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RREB1 antibody detected the RREB1 protein (arrow).

Specification

Quantity

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