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ATPIF1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APG02170G 100 μl / $495

ATPIF1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APG02170G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATPIF1 antibody (N-term).

Molecular Weight

12249 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

8-35 aa

Target

This ATPIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of human ATPIF1.

Isotype

Rabbit Ig

Symbol

ATPI

GeneID

UniProt ID

Function

Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.

Summary

This gene encodes a mitochondrial ATPase inhibitor.Alternative splicing occurs at this locus and three transcriptvariants encoding distinct isoforms have been identified. [providedby RefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

ATPase inhibitor, mitochondrial, Inhibitor of F(1)F(o)-ATPase, IF(1), IF1, ATPIF1, ATPI

Images

ATPIF1 Antibody (N-term) (Cat. APG02170G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ATPIF1 antibody detected the ATPIF1 protein (arrow).

Specification

Quantity

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