> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RAB22A Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07440G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB22A antibody (C-term).
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Molecular Weight |
21855 Da
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Cellular Localization |
Antigen Cellular Localization:
Endosome membrane; Lipid- anchor. Cell membrane; Lipid-anchor. Early endosome. Cell projection, ruffle Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
166-192 aa
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Target |
This RAB22A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-192 amino acids from the C-terminal region of human RAB22A.
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Isotype |
Rabbit Ig
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Symbol |
RAB22
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GeneID |
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UniProt ID |
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Function |
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
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Summary |
The protein encoded by this gene is a member of the RABfamily of small GTPases. The GTP-bound form of the encoded proteinhas been shown to interact with early-endosomal antigen 1, and maybe involved in the trafficking of and interaction between endosomalcompartments.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Ras-related protein Rab-22A, Rab-22, RAB22A, RAB22
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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