> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > OSCAR Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR17689G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OSCAR antibody (C-term).
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Molecular Weight |
30481 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
205-231 aa
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Target |
This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
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Summary |
Osteoclasts are multinucleated cells that resorb bone andare essential for bone homeostasis. This gene encodes anosteoclast-associated receptor (OSCAR), which is a member of theleukocyte receptor complex (LRC) protein family that plays criticalroles in the regulation of both innate and adaptive immuneresponses. Different from the other LRC members, OSCAR expressionis detected specifically in preosteoclasts or mature osteoclasts.OSCAR may be an important bone-specific regulator of osteoclastdifferentiation. Multiple alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3, OSCAR
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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