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NRXN3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM06832G 100 μl / $495

NRXN3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM06832G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NRXN3 antibody (C-term).

Molecular Weight

69305 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

436-462 aa

Target

This NRXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 436-462 amino acids from the C-terminal region of human NRXN3.

Isotype

Rabbit Ig

Symbol

KIAA0743

GeneID

UniProt ID

Function

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity).

Summary

Neurexins are a family of proteins that function in thevertebrate nervous system as cell adhesion molecules and receptors.They are encoded by several unlinked genes of which two, NRXN1 andNRXN3, are among the largest known human genes. Three of the genes(NRXN1-3) utilize two alternate promoters and include numerousalternatively spliced exons to generate thousands of distinct mRNAtranscripts and protein isoforms. The majority of transcripts areproduced from the upstream promoter and encode alpha-neurexinisoforms; a much smaller number of transcripts are produced fromthe downstream promoter and encode beta-neurexin isoforms. Thealpha-neurexins contain epidermal growth factor-like (EGF-like)sequences and laminin G domains, and have been shown to interactwith neurexophilins. The beta-neurexins lack EGF-like sequences andcontain fewer laminin G domains than alpha-neurexins. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Neurexin-3-beta, Neurexin III-beta, Neurexin-3-beta, soluble form, Neurexin-3-beta, C-terminal fragment, NRXN3-CTF, NRXN3, KIAA0743

Images

NRXN3 Antibody (C-term)(Cat. AMM06832G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NRXN3 antibody detected the NRXN3 protein (arrow).

Specification

Quantity

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