> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NRXN3 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM06832G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NRXN3 antibody (C-term).
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Molecular Weight |
69305 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
436-462 aa
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Target |
This NRXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 436-462 amino acids from the C-terminal region of human NRXN3.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0743
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GeneID |
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UniProt ID |
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Function |
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity).
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Summary |
Neurexins are a family of proteins that function in thevertebrate nervous system as cell adhesion molecules and receptors.They are encoded by several unlinked genes of which two, NRXN1 andNRXN3, are among the largest known human genes. Three of the genes(NRXN1-3) utilize two alternate promoters and include numerousalternatively spliced exons to generate thousands of distinct mRNAtranscripts and protein isoforms. The majority of transcripts areproduced from the upstream promoter and encode alpha-neurexinisoforms; a much smaller number of transcripts are produced fromthe downstream promoter and encode beta-neurexin isoforms. Thealpha-neurexins contain epidermal growth factor-like (EGF-like)sequences and laminin G domains, and have been shown to interactwith neurexophilins. The beta-neurexins lack EGF-like sequences andcontain fewer laminin G domains than alpha-neurexins. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Neurexin-3-beta, Neurexin III-beta, Neurexin-3-beta, soluble form, Neurexin-3-beta, C-terminal fragment, NRXN3-CTF, NRXN3, KIAA0743
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Images |
NRXN3 Antibody (C-term)(Cat. AMM06832G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NRXN3 antibody detected the NRXN3 protein (arrow). |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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