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HAS3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR12345G 100 μl / $495

HAS3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR12345G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HAS3 antibody (Center).

Molecular Weight

62998 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

137-164 aa

Target

This HAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human HAS3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity).

Summary

The protein encoded by this gene is involved in thesynthesis of the unbranched glycosaminoglycan hyaluronan, orhyaluronic acid, which is a major constituent of the extracellularmatrix. This gene is a member of the NODC/HAS gene family. Comparedto the proteins encoded by other members of this gene family, thisprotein appears to be more of a regulator of hyaluronan synthesis.Alternative splicing results in multiple transcript variants.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3, HAS3

Images

HAS3 Antibody (Center) (Cat. APR12345G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HAS3 antibody detected the HAS3 protein (arrow).

Specification

Quantity

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