> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SEPT6 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR11171G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPT6 antibody (C-term).
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Molecular Weight |
49717 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, spindle Chromosome, centromere, kinetochore Cleavage furrow. Midbody. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
400-426 aa
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Target |
This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0128, SEP2
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GeneID |
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UniProt ID |
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Function |
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication.
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Summary |
This gene is a member of the septin family of GTPases.Members of this family are required for cytokinesis. One version ofpediatric acute myeloid leukemia is the result of a reciprocaltranslocation between chromosomes 11 and X, with the breakpointassociated with the genes encoding the mixed-lineage leukemia andseptin 2 proteins. This gene encodes four transcript variantsencoding three distinct isoforms. An additional transcript varianthas been identified, but its biological validity has not beendetermined.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Septin-6, SEPT6, KIAA0128, SEP2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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