> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HIRIP3 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR16639G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HIRIP3 antibody (Center).
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Molecular Weight |
61957 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Note=Nuclear throughout the cell cycle and is excluded from condensed chromatin during mitosis
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
287-316 aa
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Target |
This HIRIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the Central region of human HIRIP3.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones.
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Summary |
The HIRA protein shares sequence similarity with Hir1pand Hir2p, the two corepressors of histone gene transcriptioncharacterized in the yeast, Saccharomyces cerevisiae. Thestructural features of the HIRA protein suggest that it mayfunction as part of a multiprotein complex. Recently, severalcDNAs encoding HIRA-interacting proteins, or HIRIPs, have beenidentified. In vitro, the HIRIP3 gene product binds HIRA, as wellas H2B and H3 core histones, indicating that a complex containingHIRA-HIRIP3 could function in some aspects of chromatin and histonemetabolism.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
HIRA-interacting protein 3, HIRIP3
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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