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PDE4C Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM07058G 100 μl / $495

PDE4C Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM07058G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDE4C antibody (N-term).

Molecular Weight

79902 Da

Cellular Localization

Antigen Cellular Localization: Cell projection, cilium.

Host

Rabbit

Species Reactivity

Human

Immunogen

5-31 aa

Target

This PDE4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-31 amino acids from the N-terminal region of human PDE4C.

Isotype

Rabbit Ig

Symbol

DPDE1

GeneID

UniProt ID

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Summary

Cyclic nucleotides are important second messengers thatregulate and mediate a number of cellular responses toextracellular signals, such as hormones, light, andneurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs)regulate the cellular concentrations of cyclic nucleotides andthereby play a role in signal transduction. PDE4C is a class IVcAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed8009369]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21, PDE4C, DPDE1

Images

PDE4C Antibody (N-term) (Cat. AMM07058G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PDE4C antibody detected the PDE4C protein (arrow).

Specification

Quantity

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