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PGLYRP4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG02965G 100 μl / $495

PGLYRP4 Antibody (Center)

Brand

Leading Biology

Catalog Number

APG02965G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PGLYRP4 antibody (Center).

Molecular Weight

40620 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

242-268 aa

Target

This PGLYRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the Central region of human PGLYRP4.

Isotype

Rabbit Ig

Symbol

PGRPIB

GeneID

UniProt ID

Function

Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity.

Summary

Peptidoglycan recognition proteins, such as PGRPI-beta,are part of the innate immune system and recognize peptidoglycan, aubiquitous component of bacterial cell walls.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, PGLYRPIbeta, PGRP-I-beta, Peptidoglycan recognition protein intermediate beta, PGLYRP4, PGRPIB

Images

Anti-PGLYRP4 Antibody (Center) at 1:1000 dilution + HACAT whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PGLYRP4 Antibody (Center) (Cat. APG02965G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).

Specification

Quantity

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