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CAMSAP3 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR15246G 100 μl / $495

CAMSAP3 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR15246G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAMSAP3 antibody (N-term).

Molecular Weight

134750 Da

Cellular Localization

Antigen Cellular Localization: Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton. Note=Scattered in the cytoplasm, associated with the minus-end of microtubules and also detected at the centrosomes. Localizes along zonula adherens only at mature cell-cell contacts

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

103-131 aa

Target

This CAMSAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human CAMSAP3.

Isotype

Rabbit Ig

Symbol

KIAA1543

GeneID

UniProt ID

Function

Microtubule minus-end binding protein that acts as a regulator of non-centrosomal microtubule dynamics and organization. Specifically required for the biogenesis and the maintenance of zonula adherens by anchoring the minus-end of microtubules to zonula adherens and by recruiting the kinesin KIFC3 to those junctional sites. May regulate the nucleation and the polymerization of microtubules. Indirectly, through the microtubule cytoskeleton, may regulate the organization of cellular organelles including the Golgi and the early endosomes.

Summary

Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Calmodulin-regulated spectrin-associated protein 3, Protein Nezha, CAMSAP3, KIAA1543

Images

CAMSAP3 Antibody (N-term) (Cat. APR15246G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CAMSAP3 Antibody detected the CAMSAP3 protein (arrow).

Specification

Quantity

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