> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PPIL2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07285G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPIL2 antibody (C-term).
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Molecular Weight |
58823 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Note=May also localize to the cytoplasm and the cell membrane.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
402-431 aa
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Target |
This PPIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human PPIL2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423).
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Summary |
This gene is a member of the cyclophilin family ofpeptidylprolyl isomerases. The cyclophilins are a highly conservedubiquitous family, members of which play an important role inprotein folding, immunosuppression by cyclosporin A, and infectionof HIV-1 virions. This protein interacts with the proteinaseinhibitor eglin c and is localized in the nucleus. Multipletranscript variants encoding different isoforms have been found forthis gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Peptidyl-prolyl cis-trans isomerase-like 2, PPIase, PPIL2 (HGNC:9261)
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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