> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RAB27A Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07455G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB27A antibody (C-term).
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Molecular Weight |
24868 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
136-164 aa
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Target |
This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.
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Isotype |
Rabbit Ig
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Symbol |
RAB27
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GeneID |
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UniProt ID |
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Function |
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
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Summary |
The protein encoded by this gene belongs to the smallGTPase superfamily, Rab family. The protein is membrane-bound andmay be involved in protein transport and small GTPase mediatedsignal transduction. Mutations in this gene are associated withGriscelli syndrome type 2. Alternative splicing occurs at thislocus and four transcript variants encoding the same protein havebeen identified.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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