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VAMP4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08448G 100 μl / $495

VAMP4 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08448G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VAMP4 antibody (Center).

Molecular Weight

16397 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles

Host

Rabbit

Species Reactivity

Human

Immunogen

61-90 aa

Target

This VAMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human VAMP4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.

Summary

Synaptobrevins/VAMPs, syntaxins, and the 25-kDsynaptosomal-associated protein SNAP25 are the main components of aprotein complex involved in the docking and/or fusion of synapticvesicles with the presynaptic membrane. The protein encoded by thisgene is a member of the vesicle-associated membrane protein(VAMP)/synaptobrevin family. This protein may play a role intrans-Golgi network-to-endosome transport.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Vesicle-associated membrane protein 4, VAMP-4, VAMP4

Images

VAMP4 Antibody (Center) (Cat. AMM08448G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the VAMP4 antibody detected the VAMP4 protein (arrow).

Specification

Quantity

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