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MAP2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR12494G 100 μl / $495

MAP2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR12494G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP2 antibody (C-term).

Molecular Weight

199526 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human

Immunogen

1766-1796 aa

Target

This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1766-1796 amino acids from the C-terminal region of human MAP2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Summary

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Microtubule-associated protein 2, MAP-2, MAP2

Images

Western blot analysis of hMAP2-Q425 (arrow) using rabbit polyclonal hMAP2-Q425 Antibody (RB02868). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the hMAP2-Q425 gene (Lane 2) (Origene Technologies).

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with hMAP2-Q425 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistr

Specification

Quantity

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