> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SDHB Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR07172G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SDHB antibody (C-term).
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Molecular Weight |
31630 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
205-234 aa
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Target |
This SDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.
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Isotype |
Rabbit Ig
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Symbol |
SDH, SDH1
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GeneID |
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UniProt ID |
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Function |
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
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Summary |
Complex II of the respiratory chain, which is specificallyinvolved in the oxidation of succinate, carries electrons from FADHto CoQ. The complex is composed of four nuclear-encoded subunitsand is localized in the mitochondrial inner membrane. Theiron-sulfur subunit is highly conserved and contains threecysteine-rich clusters which may comprise the iron-sulfur centersof the enzyme. Sporadic and familial mutations in this gene resultin paragangliomas and pheochromocytoma, and support a link betweenmitochondrial dysfunction and tumorigenesis.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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