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EIF4EBP2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR07671G 100 μl / $495

EIF4EBP2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR07671G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF4EBP2 antibody (C-term).

Molecular Weight

12939 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

87-115 aa

Target

This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.

Summary

This gene encodes a member of the eukaryotic translationinitiation factor 4E binding protein family. The gene products ofthis family bind eIF4E and inhibit translation initiation. However,insulin and other growth factors can release this inhibition via aphosphorylation-dependent disruption of their binding to eIF4E.Regulation of protein production through these gene products havebeen implicated in cell proliferation, cell differentiation andviral infection.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Eukaryotic translation initiation factor 4E-binding protein 2, 4E-BP2, eIF4E-binding protein 2, EIF4EBP2

Images

Western blot analysis of lysate from human brain tissue lysate, using EIF4EBP2 Antibody (C-term)(Cat. APR07671G). APR07671G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Specification

Quantity

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