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CB1 Antibody(Center)

Catalog # Availability Size / Price Inquiry
APG02451G 100 μl / $495

CB1 Antibody(Center)

Brand

Leading Biology

Catalog Number

APG02451G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CB1 antibody(Center).

Molecular Weight

52858 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

161-187 aa

Target

This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human CB1.

Isotype

Rabbit Ig

Symbol

CNR

GeneID

UniProt ID

Function

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.

Summary

This gene encodes one of two cannabinoid receptors. Thecannabinoids, principally delta-9-tetrahydrocannabinol andsynthetic analogs, are psychoactive ingredients of marijuana. Thecannabinoid receptors are members of the guanine-nucleotide-bindingprotein (G-protein) coupled receptor family, which inhibitadenylate cyclase activity in a dose-dependent, stereoselective andpertussis toxin-sensitive manner. The two receptors have been foundto be involved in the cannabinoid-induced CNS effects (includingalterations in mood and cognition) experienced by users ofmarijuana. Multiple transcript variants encoding two differentprotein isoforms have been described for this gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR

Images

CB1 Antibody (Center) (Cat. APG02451G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CB1 antibody detected the CB1 protein (arrow).

Specification

Quantity

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