> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Mouse Dyrk1a Antibody(C-term)Brand |
Leading Biology | Catalog Number |
AMM06428G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Dyrk1a antibody(C-term).
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Molecular Weight |
85494 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus speckle
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
718-745 aa
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Target |
This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
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Isotype |
Rabbit Ig
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Symbol |
Dyrk
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GeneID |
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UniProt ID |
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Function |
May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1, SRSF6 and SIRT1. Exhibits a sugstrate preference for proline at position P+1 and arginine at position P-3.
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Summary |
Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, MP86, Protein kinase minibrain homolog, MNBH, Dyrk1a, Dyrk
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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