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TGM5 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR10434G 100 μl / $495

TGM5 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR10434G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGM5 antibody (C-term).

Molecular Weight

80778 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Note=Associated with intermediate filaments

Host

Rabbit

Species Reactivity

Human

Immunogen

686-715 aa

Target

This TGM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 686-715 amino acids from the C-terminal region of human TGM5.

Isotype

Rabbit Ig

Symbol

TGMX

GeneID

UniProt ID

Function

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.

Summary

This gene encodes a member of the transglutaminase family.The encoded protein catalyzes formation of protein cross-linksbetween glutamine and lysine residues, often resulting instabilization of protein assemblies. This reaction is calciumdependent. Mutations in this gene have been associated with acralpeeling skin syndrome.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Protein-glutamine gamma-glutamyltransferase 5, Transglutaminase X, TG(X), TGX, TGase X, Transglutaminase-5, TGase-5, TGM5, TGMX

Images

All lanes : Anti-TGM5 Antibody (C-term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: ZR-75-1 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 81 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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