> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PLIN3 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM07251G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLIN3 antibody (Center).
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Molecular Weight |
47075 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet. Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
230-257 aa
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Target |
This PLIN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the Central region of human PLIN3.
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Isotype |
Rabbit Ig
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Symbol |
M6PRBP1, TIP47
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GeneID |
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UniProt ID |
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Function |
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
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Summary |
Mannose 6-phophate receptors (MPRs) deliver lysosomalhydrolase from the Golgi to endosomes and then return to the Golgicomplex. The protein encoded by this gene interacts with thecytoplasmic domains of both cation-independent and cation-dependentMPRs, and is required for endosome-to-Golgi transport. This proteinalso binds directly to the GTPase RAB9 (RAB9A), a member of the RASoncogene family. The interaction with RAB9 has been shown toincrease the affinity of this protein for its cargo. Multipletranscript variants encoding different isoforms have been found forthis gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Perilipin-3, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PP17, PLIN3, M6PRBP1, TIP47
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Images |
All lanes : Anti-PLIN3 Antibody (Center) at 1:1000 dilution Lane 1: Daudi whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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