> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TRHR Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08332G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRHR antibody (Center).
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Molecular Weight |
45085 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
209-238 aa
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Target |
This TRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human TRHR.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
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Summary |
Thyrotropin-releasing hormone (TRH; MIM 275120), a smallneuropeptide, is widely distributed throughout the central andperipheral nervous system as well as in extraneural tissues. Thepeptide is synthesized in the hypothalamus and transported by theportal vascular system to the anterior pituitary where it acts onthyrotropic and lactotropic cells to promote secretion of TSH andprolactin, respectively. Thyrotropin-releasing hormone receptor isa G protein-coupled receptor that activates the inositolphospholipid-calcium-protein kinase C transduction pathway upon thebinding of TRH. The TRHR gene is expressed in the thyrotrope cellsof the anterior pituitary.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor, TRHR
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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