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NHEDC2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR08737G 100 μl / $495

NHEDC2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR08737G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NHEDC2 antibody (C-term).

Molecular Weight

57564 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion membrane; Multi- pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

458-486 aa

Target

This NHEDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human NHEDC2.

Isotype

Rabbit Ig

Symbol

NHA2, NHEDC2

GeneID

UniProt ID

Function

Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane. Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption activity (By similarity).

Summary

Sodium hydrogen antiporters, such as NHEDC2, convert theproton motive force established by the respiratory chain or theF1F0 mitochondrial ATPase into sodium gradients that drive otherenergy-requiring processes, transduce environmental signals intocell responses, or function in drug efflux (Xiang et al., 2007[PubMed 18000046]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Mitochondrial sodium/hydrogen exchanger 9B2, Mitochondrial Na(+)/H(+) exchanger NHA2, Na(+)/H(+) exchanger-like domain-containing protein 2, NHE domain-containing protein 2, Sodium/hydrogen exchanger-like domain-containing protein 2, Solute carrier family 9 subfamily B member 2, SLC9B2, NHA2, NHEDC2

Images

NHEDC2 Antibody (C-term) (Cat. APR08737G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NHEDC2 antibody detected the NHEDC2 protein (arrow).

Specification

Quantity

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