> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > VPS37C Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM08485G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VPS37C antibody (Center).
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Molecular Weight |
38659 Da
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Cellular Localization |
Antigen Cellular Localization:
Late endosome membrane; Peripheral membrane protein. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
142-169 aa
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Target |
This VPS37C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VPS37C.
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Isotype |
Rabbit Ig
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Symbol |
PML39
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GeneID |
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UniProt ID |
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Function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
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Summary |
VPS37C is a subunit of ESCRT-I (endosomal sorting complexrequired for transport I), a complex in the class E vacuolarprotein sorting (VPS) pathway required for sorting ubiquitinatedtransmembrane proteins into internal vesicles of multivesicularbodies (Eastman et al., 2005 [PubMed 15509564]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Vacuolar protein sorting-associated protein 37C, hVps37C, ESCRT-I complex subunit VPS37C, VPS37C, PML39
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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