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MPZL2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06461G 100 μl / $495

MPZL2 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06461G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MPZL2 antibody (Center).

Molecular Weight

24484 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

67-94 aa

Target

This MPZL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human MPZL2.

Isotype

Rabbit Ig

Symbol

EVA, EVA1

GeneID

UniProt ID

Function

Mediates homophilic cell-cell adhesion.

Summary

Thymus development depends on a complex series ofinteractions between thymocytes and the stromal component of theorgan. Epithelial V-like antigen (EVA) is expressed in thymusepithelium and strongly downregulated by thymocyte developmentalprogression. This gene is expressed in the thymus and in severalepithelial structures early in embryogenesis. It is highlyhomologous to the myelin protein zero and, in thymus-derivedepithelial cell lines, is poorly soluble in nonionic detergents,strongly suggesting an association to the cytoskeleton. Itscapacity to mediate cell adhesion through a homophilic interactionand its selective regulation by T cell maturation might imply theparticipation of EVA in the earliest phases of thymusorganogenesis. The protein bears a characteristic V-type domain andtwo potential N-glycosylation sites in the extracellular domain; aputative serine phosphorylation site for casein kinase 2 is alsopresent in the cytoplasmic tail. Two transcript variants encodingthe same protein have been found for this gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Myelin protein zero-like protein 2, Epithelial V-like antigen 1, MPZL2, EVA, EVA1

Images

MPZL2 Antibody (Center) (Cat. AMM06461G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MPZL2 antibody detected the MPZL2 protein (arrow).

Specification

Quantity

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