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TBC1D10B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM08098G 100 μl / $495

TBC1D10B Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM08098G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TBC1D10B antibody (C-term).

Molecular Weight

87199 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Note=In melanocytes, located at the periphery of cells

Host

Rabbit

Species Reactivity

Human

Immunogen

781-808 aa

Target

This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A.

Summary

Small G proteins of the RAB family (see MIM 179508)function in intracellular vesicle trafficking by switching from theGTP-bound state to the GDP-bound state with the assistance ofguanine nucleotide exchange factors (GEFs; see MIM 609700) andGTPase-activating proteins (GAPs). TBC1D10B functions as a GAP forseveral proteins of the Rab family (Ishibashi et al., 2009 [PubMed19077034]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B

Images

TBC1D10B Antibody (C-term) (Cat. AMM08098G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TBC1D10B antibody detected the TBC1D10B protein (arrow).

Specification

Quantity

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