> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TBC1D10B Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM08098G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TBC1D10B antibody (C-term).
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Molecular Weight |
87199 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Note=In melanocytes, located at the periphery of cells
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
781-808 aa
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Target |
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A.
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Summary |
Small G proteins of the RAB family (see MIM 179508)function in intracellular vesicle trafficking by switching from theGTP-bound state to the GDP-bound state with the assistance ofguanine nucleotide exchange factors (GEFs; see MIM 609700) andGTPase-activating proteins (GAPs). TBC1D10B functions as a GAP forseveral proteins of the Rab family (Ishibashi et al., 2009 [PubMed19077034]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B
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Images |
TBC1D10B Antibody (C-term) (Cat. AMM08098G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TBC1D10B antibody detected the TBC1D10B protein (arrow). |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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