> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KLHL2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR17035G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLHL2 antibody (N-term).
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Molecular Weight |
65975 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol. Note=A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity)
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
77-103 aa
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Target |
This KLHL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-103 amino acids from the N-terminal region of human KLHL2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
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Summary |
KLHL2 may play a role in organizing the actin cytoskeleton of the brain cells.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Kelch-like protein 2, Actin-binding protein Mayven, KLHL2
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Images |
KLHL2 Antibody (N-term) (Cat. APR17035G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the KLHL2 antibody detected the KLHL2 protein (arrow). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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