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LY96 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR17258G 100 μl / $495

LY96 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR17258G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LY96 antibody (C-term).

Molecular Weight

18546 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space.

Host

Rabbit

Species Reactivity

Human

Immunogen

103-132 aa

Target

This LY96 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human LY96.

Isotype

Rabbit Ig

Symbol

ESOP1, MD2

GeneID

UniProt ID

Function

Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.

Summary

This gene encodes a protein which associates withtoll-like receptor 4 on the cell surface and confers responsivenessto lipopolysaccyaride (LPS), thus providing a link between thereceptor and LPS signaling. Studies of the mouse ortholog suggestthat this gene may be involved in endotoxin neutralization.Alternative splicing results in multiple transcript variantsencoding different isoforms.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2

Images

LY96 Antibody (C-term) (Cat. APR17258G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LY96 antibody detected the LY96 protein (arrow).

Specification

Quantity

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