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CD1D Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR15336G 100 μl / $495

CD1D Antibody (Center)

Brand

Leading Biology

Catalog Number

APR15336G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD1D antibody (Center).

Molecular Weight

37717 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes

Host

Rabbit

Species Reactivity

Human

Immunogen

177-206 aa

Target

This CD1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human CD1D.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Summary

This gene encodes a divergent member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to late endosomes and lysosomes via atyrosine-based motif in the cytoplasmic tail.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Antigen-presenting glycoprotein CD1d, R3G1, CD1d, CD1D

Images

CD1D Antibody (Center) (Cat. APR15336G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CD1D antibody detected the CD1D protein (arrow).

Western blot analysis of CD1D (arrow) using rabbit polyclonal CD1D Antibody (Center) (Cat. APR15336G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1D gene.

Specification

Quantity

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