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SEPT11 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13263G 100 μl / $495

SEPT11 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13263G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SEPT11 antibody (Center).

Molecular Weight

49398 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria

Host

Rabbit

Species Reactivity

Human

Immunogen

353-382 aa

Target

This SEPT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the Central region of human SEPT11.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

Summary

SEPT11 belongs to the conserved septin family offilament-forming cytoskeletal GTPases that are involved in avariety of cellular functions including cytokinesis and vesicletrafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al.,2004 [PubMed 15485874]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Septin-11, SEPT11

Images

SEPT11 Antibody (Center) (Cat. APR13263G) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SEPT11 antibody detected the SEPT11 protein (arrow).

Specification

Quantity

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