> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > P2RX1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR12644G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2RX1 antibody (C-term).
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Molecular Weight |
44980 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
345-372 aa
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Target |
This P2RX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-372 amino acids from the C-terminal region of human P2RX1.
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Isotype |
Rabbit Ig
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Symbol |
P2X1
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GeneID |
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UniProt ID |
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Function |
Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
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Summary |
The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel with relatively high calcium permeability. Binding toATP mediates synaptic transmission between neurons and from neuronsto smooth muscle, being responsible, for example, for sympatheticvasoconstriction in small arteries, arterioles and vas deferens.Mouse studies suggest that this receptor is essential for normalmale reproductive function. It is possible that the development ofselective antagonists for this receptor may provide an effectivenon-hormonal male contraceptive pill.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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