> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ARHGEF6 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR15030G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ARHGEF6 antibody (C-term).
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Molecular Weight |
87499 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell projection, lamellipodium
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
614-641 aa
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Target |
This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
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Isotype |
Rabbit Ig
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Symbol |
COOL2, KIAA0006, PIXA
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GeneID |
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UniProt ID |
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Function |
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
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Summary |
Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein belongs toa family of cytoplasmic proteins that activate the Ras-like familyof Rho proteins by exchanging bound GDP for GTP. It may form acomplex with G proteins and stimulate Rho-dependent signals. Thisprotein is activated by PI3-kinase. Mutations in this gene cancause X-chromosomal non-specific mental retardation. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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