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LIMA1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR17197G 100 μl / $495

LIMA1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR17197G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIMA1 antibody (N-term).

Molecular Weight

85226 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=This cytoskeletal protein co- localizes with actin stress fibers and focal adhesion plaques

Host

Rabbit

Species Reactivity

Human

Immunogen

135-163 aa

Target

This LIMA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the N-terminal region of human LIMA1.

Isotype

Rabbit Ig

Symbol

EPLIN, SREBP3

GeneID

UniProt ID

Function

Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.

Summary

EPLIN is a cytoskeleton-associated protein that inhibitsactin filament depolymerization and cross-links filaments inbundles (Maul et al., 2003 [PubMed 12566430]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

LIM domain and actin-binding protein 1, Epithelial protein lost in neoplasm, LIMA1, EPLIN, SREBP3

Images

LIMA1 Antibody (N-term) (Cat. APR17197G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow).

Specification

Quantity

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