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NUDC Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06864G 100 μl / $495

NUDC Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06864G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NUDC antibody (Center).

Molecular Weight

38243 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern

Host

Rabbit

Species Reactivity

Human

Immunogen

105-133 aa

Target

This NUDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the Central region of human NUDC.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.

Summary

NudC was first identified as a regulator of nuclearmovement in the asexual reproductive cycle of the filamentousfungus Aspergillus nidulans. Human NUDC is a nuclear movementprotein that associates with dynein (see DYNC1H1; MIM 600112)(Aumais et al., 2003 [PubMed 12679384]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Nuclear migration protein nudC, Nuclear distribution protein C homolog, NUDC

Images

NUDC Antibody (Center) (Cat. AMM06864G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NUDC antibody detected the NUDC protein (arrow).

Specification

Quantity

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