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STC1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR10288G 100 μl / $495

STC1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR10288G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STC1 antibody (C-term).

Molecular Weight

27621 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

193-221 aa

Target

This STC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the C-terminal region of human STC1.

Isotype

Rabbit Ig

Symbol

STC

GeneID

UniProt ID

Function

Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.

Summary

This gene encodes a secreted, homodimeric glycoproteinthat is expressed in a wide variety of tissues and may haveautocrine or paracrine functions. The gene contains a 5' UTR richin CAG trinucleotide repeats. The encoded protein contains 11conserved cysteine residues and is phosphorylated by protein kinaseC exclusively on its serine residues. The protein may play a rolein the regulation of renal and intestinal calcium and phosphatetransport, cell metabolism, or cellular calcium/phosphatehomeostasis. Overexpression of human stanniocalcin 1 in miceproduces high serum phosphate levels, dwarfism, and increasedmetabolic rate. This gene has altered expression in hepatocellular,ovarian, and breast cancers.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Stanniocalcin-1, STC-1, STC1, STC

Images

STC1 Antibody (C-term) (Cat. APR10288G) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the STC1 antibody detected the STC1 protein (arrow).

Specification

Quantity

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