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DSG3 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM06960G 100 μl / $495

DSG3 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM06960G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DSG3 antibody (N-term).

Molecular Weight

107533 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome

Host

Rabbit

Species Reactivity

Human

Immunogen

8-36 aa

Target

This DSG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human DSG3.

Isotype

Rabbit Ig

Symbol

CDHF6

GeneID

UniProt ID

Function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Summary

Desmosomes are cell-cell junctions between epithelial,myocardial, and certain other cell types. Desmoglein 3 is acalcium-binding transmembrane glycoprotein component of desmosomesin vertebrate epithelial cells. Currently, three desmogleinsubfamily members have been identified and all are members of thecadherin cell adhesion molecule superfamily. These desmoglein genefamily members are located in a cluster on chromosome 18. Thisprotein has been identified as the autoantigen of the autoimmuneskin blistering disease pemphigus vulgaris.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6, DSG3, CDHF6

Images

All lanes : Anti-DSG3 Antibody (N-term) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: HACAT whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 108 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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