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P2RY1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR12667G 100 μl / $495

P2RY1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR12667G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2RY1 antibody (Center).

Molecular Weight

42072 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

231-260 aa

Target

This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

Summary

The product of this gene belongs to the family ofG-protein coupled receptors. This family has several receptorsubtypes with different pharmacological selectivity, which overlapsin some cases, for various adenosine and uridine nucleotides. Thisreceptor functions as a receptor for extracellular ATP and ADP. Inplatelets binding to ADP leads to mobilization of intracellularcalcium ions via activation of phospholipase C, a change inplatelet shape, and probably to platelet aggregation. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1

Images

P2RY1 Antibody (Center) (Cat. APR12667G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the P2RY1 antibody detected the P2RY1 protein (arrow).

Specification

Quantity

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